US overdose deaths slowly declined in 2025, data shows

While fentanyl is not a natural opioid, the fentanyl chemical structure means its reaction in the body mimics an opioid. When it enters the body, fentanyl will attach to the same pain receptors as opioids and block them. This creates an increase in pleasure sensations in the body, or the “euphoric” effect. Fentanyl was first […]